|
KMID : 0861020070220040187
|
|
Korea Journal of Herbology
2007 Volume.22 No. 4 p.187 ~ p.199
|
|
|
The Comparative Study of the Effects of Fructificatio Inonoti Obliqui Aqueous Extract according to the Extraction Temperature(II) -Anti-oxidativy Activity, anti inflammatory effect and cancer cell multiplication inhibition effect-)
|
|
Park Kyu-Cheon
Lee Young-Jong
Han Hyo-Sang
|
|
|
Abstract
|
|
|
Objectives : The present study purposed to compare the antioxidant effect, anti inflammatory effect and cancer cell multiplication inhibition effect of Fructificatio Inonoti Obliqui aqueous extract according to extraction temperature.
Methods : We medicated animal models, which had experimental oxidation, with Fructificatio Inonoti Obliqui total extract and 50 {circ}C low temperature leachate, and performed hematological analysis and blood chemical analysis with measuring SOD, GSH, catalase, NO and MDA content in the liver. In addition, we made comparative observation of anti inflammatory effect and anti-cancer effect.
Results : Compared to the control group, both the group medicated with Fructificatio Inonoti Obliqui total extract and with 50 {circ}C low-temperature leachate were found to decrease the number of thrombocytes in blood plasma and NO content while to increase SOD activity and catalase activity significantly. Both groups also showed anti-inflammatory effect against THP-1 cells and a multiplication inhibition effect against liver cancer cells and stomach cancer cells significantly.
Conclusions : Both Fructificatio Inonoti Obliqui total extract and Fructificatio Inonoti Obliqui 50 {circ}C low-temperature leachate have significant antioxidant effect, anti inflammatory effect and anti cancer effect.
|
|
|
KEYWORD
|
|
|
Inonotus obliquus, Fructificatio Inonoti Obliqui, anti-oxidative effect, anti-inflammatory effect, anti-cancer effect
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|